Polynucleotides vs exosomes
Two of the most talked-about regenerative treatments, what each one actually does, and how we choose between them.
They are often mentioned in the same breath, and they do share a goal: better skin built from within rather than resurfaced from above. But they work by different mechanisms, and the right choice depends on you.
What polynucleotides do
Polynucleotides are purified DNA fragments, usually from salmon, delivered into the skin by fine needle. As they break down they release nucleotides that fibroblasts use as raw material, while quietening inflammation and improving hydration. They are particularly strong under the eye and on the neck, where the skin is thin and difficult to treat.
What exosomes do
Exosomes are signalling vesicles. Applied topically after microneedling, they prompt the skin's own cells to behave more like younger ones, producing more collagen and elastin. The effect is a quality and tone improvement across the treated area.
How we choose
For a specific, delicate concern such as crepey under-eye skin, polynucleotides often win. For overall skin quality and tone, exosome therapy is usually the better starting point. Many clients do best on a sequence that uses both. We decide at consultation, based on your skin rather than a menu.
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